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To put this in perspective, a 175 lb (79 kg) person receiving an equivalent dose would be taking over 1,500 mg, roughly 3,000 times the typical human research dose

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PINK1 deficiency in microglia has been linked to increased production and secretion of pro-inflammatory mediators, coupled with a reduction in the production and secretion of anti-inflammatory factors thereby favouring a reactive phenotype in microglia (44)

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