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The olfactory epithelium in the upper nasal cavity is served by olfactory nerve axons that travel through the cribriform plate directly to the olfactory bulb, bypassing the BBB

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For those who do not have a deficiency, there is a lack of evidence that supplementing vitamin C would prevent COVID-19 infection and further studies would need to be performed for a compelling case to be made that it is a feasible prophylactic option