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The main critics of this training modality point out that shorter rest periods and exercise to failure might reduce the total training volume, which is a valid concern

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Fifteen trials have investigated combinations of Phyllanthus and antiviral drugs (INF-α, lamivudine, adefovir dipivoxil, thymosin, vidarabine), and demonstrated significant improvements associated with combination therapy over antiviral drugs alone, such as reducing blood levels of HBV DNA & HBV antigen, and increasing immune response to HBV (Xia 2011)