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Morning vs evening injections Morning injections mean any initial side effects (nausea, headache , fatigue ) peak during the day when you are awake and can manage them

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Based on the amount of melatonin marketed globally per year (estimated to be $2.8 billion in 2025), there are thousands of individuals who take melatonin on a regular basis, likely over a very large dose range, who could be retrospectively studied (23)