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Significant healing needs that affect quality of life may justify accepting theoretical risks that would be unacceptable for minor issues

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The mechanism that links lipogenesis with phagocytosis was later elucidated by Lee et al., who showed that phagocytosis was impaired in LPS-activated Mφs isolated from mice deficient in sterol regulatory element binding protein 1a (SREBP-1a) (19), which regulates the transcription of genes related to lipogenesis (20)