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Introduction Programed cell death is critical to all aspects of mammalian growth and development, homeostatic regulation, and disease control and is closely integrated with other biological processes to sustain life

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In photooxidation reactions, the chromophore in the eye absorbs light and produces free radicals such as singlet oxygen, superoxide, and hydroxyl radical, which cause lipid peroxidation, leading to damage to the integrity of biological membranes, resulting in ocular tissue damage and macular degeneration