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the opposite side is injected with the same number of units to maintain facial symmetry“follow-the-pain” injections in areas where the individual reports that pain exists (additional sites in V1, V2, V3, and temporalis): 2.5 to 5 units at each site Between 50 and 100 units used every 3 months, although individuals have benefited from lower doses Dose adjustments can be made depending on clinical response or facial weakness

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The primary mechanism involves myelin synthesis and maintenance