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(Kraus et al., 2014) reported an increase in NNMT expression levels in the livers and WATs of T2D mice

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Mitochondria from the two younger groups were found to be numerous, regular in size, and with round or oval shapes ( 2+ concentration, and increased Ca 2+ sequestration in the mitochondria in cells with advanced aging ( FIGURE 2 There are several reports regarding age-related mitochondrial changes in animal models of RPE aging