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Hier ist eine hohe und zuverlässige systemische – oder besser noch lokale – Verfügbarkeit am Zielgewebe gefragt, und genau das leistet die Injektion am verlässlichsten

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Since normal epithelial barrier function is determined in part by the integrity of the AJC, it was initially hypothesized that defects in this structure, made of tight junctions and adherens junctions, led to alterations in intestinal permeability seen in cases of IBD