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Another commenter supported excluding physical therapists and recommended that CMS explore future iterations of value-based models that allow direct participation by physical therapists in ways that are financially and structurally feasible

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In parallel to the suppression of transcription factors, mRNA expression of markers of adipose differentiation such as adiponectin, leptin, resistin and adipsin, which are all humoral factors derived from adipose tissue, were decreased 60–90% [13]