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HUGE NEWS! The FDA has approved UCB's Kygevvi (doxecitine and doxribtimine) to treat the mitochondrial disease thymidine kinase 2 deficiency (TK2d). You can find the full prescribing details and announcement at https://bit.ly/4hH4Yhr

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Another example of a compound with toxicity to both parasites and patients is amphotericin B, which is used in the treatment of leishmaniasis and has been shown to be nephrotoxic