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[74] Medical uses The Pfizer–BioNTech COVID-19 vaccine is used to provide protection against COVID-19, caused by infection with the SARS-CoV-2 virus, by eliciting an immune response to the S antigen

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keloid fibroblasts were prone to senescence following an ischemic stimulus, and FOXO4-DRI selectively induced the apoptosis of keloid senescent fibroblasts via p53-pS15 translocation from the nucleus to the cytoplasm