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Shots earn their place in: Severe neurological deficiency where you want repletion fast Malabsorption after gastrectomy, sleeve, bypass, or ileal resection Pernicious anemia in someone who won’t take a daily tablet reliably Severe symptomatic anemia Anyone who can’t swallow or absorb anything orally Outside those, here’s my opinion, stated plainly: for the average person getting weekly injections for “energy” without a documented deficiency, the shot adds cost, needle risk, and side effect exposure without adding a single measurable benefit over a $12 bottle of tablets

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By blocking the primary “drain” on cellular NAD+, researchers can observe enhanced mitochondrial function and improved resistance to metabolic stress