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1 Lumbar/intervertebral disc degeneration (IDD) is one of the most common diagnoses involved in LBP and results in lumbar instability and height loss, which in turn leads to symptomatic nerve compression, intervertebral foramen stenosis, adjacent segment degeneration, and instability-induced LBP

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Maintenance immunosuppressive therapy included tacrolimus (at 6–8 ng/mL target concentration), glucocorticoids, and mycophenolic acid preparations