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Therapeutic approaches in MS that promote maturation of OPCs into mature oligodendrocytes or improve oligodendrocyte survival could generate oligodendrocytes that provide trophic support to neurons, for example, by improving the oligodendrocyte-neuron interaction, even without directly regulating the mechanisms (described in previous sections) that affect oligodendrocyte metabolic support

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[DOI] [PubMed] [Google Scholar] 28.Li G., Qin Y., Cheng Z., Cheng X., Wang R., Luo X., Zhao Y., Zhang D., Li G