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Nonetheless, key questions regarding immune-mediated mechanisms in the cardiovascular microenvironment remain unresolved: 1) How do mitochondrial stress and neutrophil extracellular traps (NETs) specifically regulate the activation of the cGAS–STING pathway and its downstream type I interferon response at different stages of AS

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Nevertheless, further studies are needed to evaluate the efficiency and safety of Syn ® -Ake for a better understanding of the way this peptide can be incorporated into cosmetic products [70]