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If you are concerned about acne whilst taking B12 supplements, it is advisable to discuss this with your GP rather than discontinuing treatment without medical guidance, particularly if the B12 has been prescribed to address a documented deficiency
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Compounders have not shared any data on the new molecule produced from the interaction of tirzepatide and vitamin B12, “so we don’t know what its safety profile is or whether it could affect how well the medication works,” Moreno says