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Across human macrophage models and rodent LPS-challenge systems, sulforaphane-mediated Nrf2 activation reduces intracellular reactive oxygen species, attenuates NF-κB signaling, and lowers pro-inflammatory cytokine release, including TNF-α and IL-6 (Yan and Yan, 2023

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The production of exophers in this study reflects the extrusion of native neuronal contents, as no fluorescent transgene is introduced

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