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Inducing pyroptosis in tumors has been shown to promote immune clearance 10,11,12 , and several small-molecule therapies targeting this pathway are approved chemotherapies 13
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Results: Cirrhotic animals receiving LPA pathway inhibitors exhibited lower portal pressure compared to vehicle-treated rats (ATXi: 13.4 Β± 0.5 Vs 15.1 Β± 0.6 mmHg