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In addition, during differentiation of neuroblastoma cells, it has been shown that a protein kinase A (PKA) activator will increase the quantity of NAAG, while a protein kinase C (PKC) activator will decrease its concentration
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There is some evidence that SGLT-2 inhibitors may affect plasma levels of Vitamin D and PTH which in turn have adverse effects on bone metabolism (Blau & Taylor, 2018)