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Of particular interest is the age-related expansion of in proinflammatory monocyte subsets (CD14+CD16+ intermediate and CD14 dim CD16 bright non-classical) bearing characteristics of cellular senescence such as telomere shortening and constitutive cytokine production (65, 66)

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"While it has largely been the case that COVID-19 tends to be less severe in children than adults, the omicron wave has seen more kids getting sick with the disease and being hospitalized, and children may also experience longer term effects, even following initially mild disease," FDA Commissioner Dr