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Footnotes Abbreviations: CKD chronic kidney disease DGAT2 diglyceride acyltransferase 2 ESRD end-stage renal disease NAM nicotinamide NAMPT nicotinamide phosphoribosyltransferase NNMT nicotinamide N -methyltransferase NR nicotinamide riboside PARP poly(ADP-ribose)-polymerase PGC-1α peroxisome proliferator-activated receptor gamma coactivator 1-α SIRT1 sirtuin 1 TG triglyceride This work was supported by European Research Council Grant ERC-2017-ADG-787702, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung Grant SNSF 31003A_179435, and the École Polytechnique Fédérale de Lausanne
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Stevens, T