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The adenosine metabolite inosine is a functional agonist of the adenosine A2A receptor with a unique signaling bias

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While this may seem obvious in principle, the preference of Type II diabetic patients for a once-daily oral tablet over a once-weekly sub-cutaneous (SC) injection of the anti-diabetic Glucagon-like peptide 1 (GLP-1) analogue, semaglutide (Ozempic®), may not be quite so clear-cut when the dosing issues around food interactions are considered