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IGF-1 LR3 (Insulin-Like Growth Factor-1, Long R3) Long-acting insulin-like growth factor-1 (IGF-1) analogue (investigational) · Pre-filled pen IGF-1 LR3 is a structurally modified, long-acting analogue of IGF-1 that engages the IGF-1 receptor (IGF-1R) and downstream anabolic cascades such as PI3K/AKT/mTOR and MAPK

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[DOI] [PMC free article] [PubMed] [Google Scholar] 55.Giegerich A.K., Kuchler L., Sha L.K., Knape T., Heide H., Wittig I., Behrends C., Brune B., von Knethen A