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Cys can also perform a direct chelation of metals (such as Cd) by synthesizing methionine and GSH/PCs that in turn can sequester metals and provide a higher antioxidant defense in plants (Dominguez-Solis et al., Conclusions and future prospects Plant tolerance to metal-load-accrued impacts largely decides the efficiency and success of a metal-remediation system (Vangronsveld et al., 2009