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Microglia M1 polarization switches to glycolytic metabolism and further amplifies neuroinflammation through HIF-1α-dependent pathways [159]
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Dieterich, Icahn School of Medicine at Mount Sinai, New York, NY, Stephen A Harrison, Pinnacle Clinical Research Center, San Antonio, TX and Mazen Noureddin, Houston Research Institute, Houston, TX Background: NAFLD affects approximately 30% of the US population and up to 25% of patients with NAFLD progress to NASH