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Stacked on top of insulin or a sulfonylurea it can, and the lever is de-intensifying that background drug, not lowering the tirzepatide dose.¹³ Over-loss in low-BMI deep responders Across the obesity trials, about 7% of participants fell below a BMI of 22, some by week 12

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Together, these elements are rungs on a ladder taking you up to one goal: maintaining your health in a holistic way—physically, mentally, and emotionally—so you can truly thrive throughout perimenopause, menopause, and well into the future