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GHRH receptors have been described in primary as well as clonal pancreatic beta-cells (insulinoma cells) and isolated islets ( Interestingly, the discovery of GHRH was due in part to the recognition of ectopic GHRH secretion from human pancreatic islet tumors causing ectopic acromegaly ( Despite these advances, the details of GHRHR expression, signaling pathways, and function in pancreatic islet cells have not been fully elucidated

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Additional testing can help identify those abnormalities