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To successfully discriminate the regions in MRP1 that selectively control the stimulated mode of GSH transport from the basal transport of GSH, we decided to follow the strategy of chimera constructs to localize and characterize the substrates-binding sites 19,20

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Points clés à retenir Avant d’entrer dans les détails, il est utile de garder quelques idées en tête pour mieux comprendre la suite