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Rheumatoid Arthritis: Symptoms, Causes and Support Strategies

This review systematically summarizes the molecular mechanisms underlying the dynamic equilibrium of cellular redox state, including the intracellular sources of ROS and the multilayered antioxidant defense network

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Research indicates that gut microbial metabolites, such as SCFAs and α-tocopherol, can activate various G protein-coupled receptors (e.g., FFAR2, OLF78, GPBAR1) on the surface of EC cells, thereby promoting the expression of tryptophan hydroxylase 1 (TPH1) and the release of 5-HT (252–255)