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Consistently, in the current study, only 5.88% of patients in l-ARG group experienced adverse effects (including gastric pyrosis, urticarial reaction and scrotal itching), but none of which was manifested as clinically relevant, and did not induce treatment discontinuation

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Additionally, we performed molecular docking studies involving CTNNB1 and anwuligan, which revealed a moderate binding affinity between the two entities (affinity = −5.6 kcal/mol) (Figure 1C)