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It is a disease that occurs due to mutations in the gene encoding for the CF transmembrane conductance regulator (CFTR)

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36 : 431–441 Zinszner H, Kuroda M, Wang XZ, Batchvarova N, Lightfoot RT, Remotti H, Stevens JL and Ron D (1998) CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum