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The role of macrophages in AS is thought to be inseparable from the polarization and phenotypic expression of macrophages

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Research demonstrates GHK-Cu modulates over 4,000 human genes, stimulates collagen I, III, and elastin synthesis, activates matrix metalloproteinases for extracellular matrix remodelling, promotes wound contraction and angiogenesis, and suppresses pro-inflammatory TNF-α signalling