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Baker’s notes & crumb story
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Glucuronidation involves the metabolism of parent compound by UDP-glucuronosyltransferases (UGTs) into hydrophilic and negatively charged glucuronides that cannot exit the cell without the aid of efflux transporters
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Indeed, according to the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-V), diagnosis of ASD is solely based on behavioral changes, and the behavior of a mouse is not the same as the behavior of a child or adult [1]