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3,4 In contrast, in Parkinson's disease (PD), neuronal deposits of α-synuclein are present and form the primary structural component of Lewy body fibrils that are characteristic of the disorder, whereas in Huntington's disease (HD), cytoplasmic and nuclear deposition of the huntingtin protein and fragments thereof are found

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Conclusion: In this large population sample, the SAFE score was predictive of liver, cardiovascular and mortality outcomes, which may indicate that the inclusion of metabolic variables affords the SAFE score additional refinement to the prediction by FIB-4