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doi: 10.1016/j.cmet.2019.05.007

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197 Likewise, H3K9la in head and neck squamous cell carcinoma (HNSCC) cell lines initiates IL-11 expression, which transcriptionally activates immune checkpoint genes through JAK2/STAT3 signaling in CD8 + T cells, diminishing CD8 + T-cell killing and weakening the immunotherapy response

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