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For example, protonated polymers such as chitosan and tannic acid can release antimicrobial substances under acidic gastric conditions

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1 Introduction Diabetic kidney disease (DKD) is one of the most common and severe microvascular complications of diabetes mellitus, representing the leading cause of end-stage renal disease (ESRD) worldwide ( The pathogenesis of DKD is extremely complex, involving dysregulation of multiple metabolic pathways