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Another study investigating the effects of 4-HNE on cardiomyocyte DNA repair capacity reported that the activity of 8-oxoguanine DNA glycosylase 1 (OGG1), a key enzyme responsible for repairing oxidative DNA damage, was significantly reduced in the myocardium of db/db mice, accompanied by elevated 4-HNE adduct levels

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Besides, this inhibitory effect of SL is dose-dependent at concentrations ranging from 10 to 25 μg/mL

where they are burned for energy