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For instance, studies found increased IL-1 beta in cerebrospinal fluid from individuals with BD and, in postmortem studies, higher levels of nuclear factor-kB (NF-kB), IL-1 receptor, glial fibrillary acidic protein (GFAP), and mRNA levels of IL-1 beta in the brains of individuals with BD compared to healthy volunteers (Rao et al., 2010)

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Natural interventions such as selenium and green tea may help protect the liver from damage