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Intracerebroventricular injection of α-MSH in awake rats increased central venous pressure and heart rate within 1 h, and they returned to baseline levels after 2 h, which may be associated with sympathetic activation (74)

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doi: 10.1038/ni.2166 529 SmithMBHaneyEMcDonaghMPappasMDaegesMWassonNet al