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These medications illustrate the core tension running through longevity medicine: they are prescription drugs with FDA approval for specific, well-established conditions, but their use in healthy-aging contexts represents off-label prescribing grounded in research interest rather than proven longevity outcomes in humans
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doi: 10.1161/circulationaha.123.065827 30 CamajaniEFeracoAVerdeLMoriconiEMarchettiMColaoAet al