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Hunger varies by patient and treatment plan

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Importantly, combination strategies demonstrate significant advantages, such as ferroptosis inducers combined with immunotherapy establishing an “immune–ferroptosis” positive feedback loop, co-treatment with radiotherapy enhancing lipid peroxidation through multiple pathways, and integration with nanodelivery systems enabling tumor-targeted therapy while minimizing systemic toxicity, all of which provide multifaceted solutions to overcome treatment resistance

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