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In trauma-induced injuries (Köbner), treatment with topical corticosteroids and tacrolimus reduced the underlying inflammatory infiltrate.96 Phototherapy, in addition to stabilizing the redox balance, suppresses the inflammatory response, promoting T-cell apoptosis, decreasing inflammatory cytokines, increasing IL10 (with regulatory T-cell induction), reducing JAK1 expression, and depleting the Langerhans cells of the epidermis.97 Vitiligo induced by chemical agents Chemical-associated vitiligo, also called leukoderma, has been described especially in rubber industry workers in contact with phenolic compounds