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Upregulation of the major histocompatibility complex II (MHCII) protein in CNS myeloid cells and recruitment of CD4+ and CD8+ T cells into the CNS occur due to α-syn accumulation (Williams et al., 2021)

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105,119 Compared with some other nanoparticle materials, nanosilica has a well-documented ability to mobilize the immune/inflammatory and stress response networks of the body