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The decreased alcohol-induced NAD + :NADH redox ratio has profound effects on liver metabolic pathways, affecting glycolysis, fatty acid oxidation, gluconeogenesis, pyruvate dehydrogenase, and the citric acid cycle as well as promoting a highly reduced cytosolic environment that, in turn, increases susceptibility to damage by alcohol metabolites (21)

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What Do Microglia Really Do in Healthy Adult Brain

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