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The mutant-dependent splicing alterations could arise from direct effects of compromising normal FUS/TLS splicing activity or indirectly through dysregulation of SMN function and/or through other RBPs, which are targets of FUS/TLS
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Occupational Therapist (OT) or Physical Therapist (PT) OTs and PTs will work with you to improve and maintain the ability of your joints to move, to strengthen weak muscles and to find ways to improve how you do daily activities after your injury