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The 5-on, 2-off structure already builds in rest days, so a single missed weekday has minimal impact on the overall protocol
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Targets for clear cell renal cell carcinoma include the NF-κB agonists IκB kinase b and caspase recruitment domain protein 9 (CARD9), MAPK1, fibronectin, collagen IV, RpB1 (the large subunit of RNA polymerase II), human antigen R (HuR), and Akt (also known as protein kinase B)[62]