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The following antibodies were used in this study: rabbit anti-phospho-Rb (Ser780) antibody (9307) from Cell Signaling Technology and mouse anti-β-tublin antibody (T7816) from Sigma-Aldrich Co., Llc

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Vitamin B12 deficiency is common in those with epilepsy, either as a cause or as a result of treatment with anti-epileptic drugs (Youness, etal, 2020