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On the cell membrane, FPN1, as the only protein known to transport non-heme iron out of cells, transports excessive Fe 2+ out of cells to keep intracellular Fe 2+ concentration within the normal range (Bu et al

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Evaluations after established hepatotoxicity and liver failure Because the overwhelming majority (∼90%) of patients with APAP hepatotoxicity will recover spontaneously from their acute ingestion and instead require appropriate therapy, with intensive care monitoring using cardiac telemetry and frequent laboratory checks