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Furthermore, the condition of heatstroke has been demonstrated to induce an increase in the proportion of gut microbiota such as Bacteroidetes/Firmicutes, whose reduced production of short-chain fatty acids (SCFAs) has been shown to further exacerbate systemic inflammation (Huang et al., 2023)

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For instance, humans synthesize CoQ 10 with ten isoprene units, mice produce CoQ 9 , Escherichia coli synthesizes CoQ 8 , and Saccharomyces cerevisiae generates CoQ 6 28,32,33